不同年龄大肠息肉患者的临床病理特征分析

Clinical Analysis of Pathological Characteristics about Colorectal Polyps at Different Ages

目的:探讨不同年龄段大肠息肉的临床及病理特点。方法:选取经电子结肠镜检查确诊大肠息肉并行内镜下息肉切除的患者182例,根据年龄分组,老年组(年龄≥60岁)98例,检出息肉121枚,中青年组(年龄<60岁)84例,检出息肉97枚。将老年组和中青年组的性别构成、息肉数量、部位、形态、病理类型及CEA值进行回顾性分析。结果:中青年组男性大肠息肉发生率高于老年组,差异具有统计学意义(P<0.01);老年组远端结肠息肉发生率高于中青年组,差异显著(P<0.05);中青年组直径在0.5-1.0 cm的息肉枚数明显高于老年组,而老年组山田I型息肉枚数明显高于中青年组,具有统计学意义(P<0.05);两组患者腺瘤性息肉的发生率明显高于其他类型息肉,尤其以管状腺瘤为高发;两组间CEA值均部分升高,但无统计学差异(P>0.05)。结论:应根据不同年龄组大肠息肉的临床和病理特点,采取相应诊疗方案。

Objective： To compare the clinical and pathological characteristics of colorectal polyps at different ages. Methods： 182 cases of colorectal polyps were confirmed by the electronic colonoscopy were enrolled and divided into two groups： elderly group （age ≥ 60 years, n=98） and young group （age〈60 years, n=84）. The gender composition, polyp number, location, morphology, pathological types and carcinoembryonic antigen were compared between elderly group and young group. Results： The proportion of male in young group was higher than elderly group （P〈0.05）. The incidence of distal colon polyps was higher in elderly group than in young group （P 〈0.05）. The incidence of Yamada I in elderly group were significantly higher than in young group. The incidence of adenomatous polyps was significantly higher than other histological types of polyps in elderly group and young group, particularly the tubular gland tumor. The value of CEA were partly higher in patients, but there was no significant difference between two groups. Conclusion： We should choose corresponding endoscopic screening, diagnosis and treatment according to different clinical and pathological characteristics of colorectal polyps for different age patients.