七氟醚在小儿手术麻醉诱导中的应用

Application of sevoflurane in pediatric anesthesia inductio

目的：观察七氟醚吸入在小儿麻醉诱导的临床应用。方法选取本院2012年1月~2013年12月全麻下行手术患儿120例，随机分为七氟醚组和氯胺酮组，观察记录给予麻醉后疼痛反射消失时间、睫毛反射消失时间、停药至清醒时间（睁眼或体动）。结果七氟醚组停药至清醒时间明显短于氯胺酮组，差异有统计学意义（P〈0.05）：七氟醚组疼痛反射消失时间、睫毛反射消失时间与氯胺酮组比较差异无统计学意义（P〉0.05）。结论七氟醚在小儿麻醉诱导起效快，对患儿呼吸循环影响小，术后麻醉苏醒快，值得临床推广。

Objective To investigate the clinical application of sevoflurane in pediatric inhalation anesthesia induction. Methods From January 2012 to 2013 December 120 cases operation under general anesthesia in our hospital, were randomly divided into sevoflurane group and ketamine group, observe and record the anesthesia, pain reflex time, loss of eyelash reflex time, stops the medicine to sober up time （eyes open or body movement）. Results Sevoflurane group stops the medicine to waking time was shorter than the ketamine group, the difference was statistically significant （P＆lt;0.05）： sevoflurane group pain reflex time, loss of eyelash reflex time and ketamine group had no significant difference （P＆gt;0.05）. Conclusion Sevoflurane has a rapid onset in pediatric anesthesia induction, effect on respiratory circulation is small, postoperative anesthesia recovery fast, so it is worth clinical promotion.