超声检查甲状腺结节钙化及微钙化对甲状腺癌鉴别诊断的临床意义

Clinical significance of ultrasound in diagnosis of thyroid nodule calcification and microcalcification

目的探讨超声检查对甲状腺结节钙化和微钙化检查的临床意义。方法回顾性分析甲状腺结节患者121例的病理结果及超声检查结果,分析钙化和微钙化对判断甲状腺结节良恶性的意义。结果检测出钙化的患者32例,其中9例为恶性,占28.1%;无钙化的患者共89例,其中恶性2例,占2.2%,两组比较,差异有统计学意义(P<0.01)。微钙化共21例,其中8例为恶性,占38.1%,粗钙化共11例,其中1例为恶性,占9.1%,两组比较差异有统计学意义(P<0.01)。结论超声检查甲状腺结节钙化,尤其是微钙化,对鉴别诊断甲状腺结节的良恶性具有一定的指导意义。

Objective To discuss clinical significanc of ultrasound in diagnosis of thyroid nodule calcification and microcalcification. Methods Selected 121 cases with thyroid nodule were retrospective analyzed.Clinical significance of calcification and microcalcification in differential diagnosis of benign and malignant nodules were analyzed. Results 32 cases showed calcification detected by ultrasound. Among them, 9 cases were malignant,accounted for 28.1%. Among 89 cases without calcification,2 cases were malignant,accounted for 2.2%. There were significant differences between two groups（P〈0.01 ）. Among 21 cases with microcalcification, 8 cases were malignant, accounted for 38.1%. Among 11 cases with coarser calcification,1 case was malignant,accounted for 9.1%. There were significant differences between two groups （P〈0.01）. Conclusion Ultrasound for thyroid nodule calcification, especially microcalcification, shows significance in differential diagnosis of benign and malignant nodules.