62例早发型重度子痫前期的临床分析

Clinical analysis about early-onset severe preeclampsia of 62 cases

目的探讨期待治疗对早发型重度子痫前期母婴预后的影响。方法对本院62例早发型重度子痫前期进行回顾性研究。根据患者发病孕周分成3组:A组(22例):n<28周,B组(24例):28周≤n<32周、C组(16例):32周≤n<34周。结果 A、C两组期待治疗时间短于B组,差异均具有统计学意义(P<0.05);三组患者随发病孕周的增加,并发症发病率减小,而三组间无显著性意义(P>0.05);三组随发病孕周的延长,新生儿的窒息率和围产儿的死亡率均下降,且均具有显著性意义(P<0.05);剖宫产是三组患者主要的分娩方式。结论早发型重度子痫前期对母儿预后有严重的影响,积极采取期待治疗措施,可适当的延长孕周,使围产儿结局得到改善;剖宫产是终止妊娠的首选方式。

Objective To study the effect of expectant treatment on the maternal and neonatal outcome of early-onset severe preeclampsia. Methods A retrospective analysis was carried out on 62 patients with early-onset severe preeclampsia. They were divided into three groups according to pathogenic week of gestation ： group A （n〈28 weeks, 22 cases ）;group B （28 weeks≤n〈32 weeks, 24 cases）;group C （32 weeks≤〈n〈34 weeks, 16 cases）. Results Expectant treatment time of group B was longer than that of the other groups, and there was significance in statistics （P〈 0.05）; The rates of pregnant complications in early-onset severe preeclampsia declined following along with the post ponement of pathogenic week of gestation, but there was no significant differences of three groups （P〉0.05）; The neonatal asphyxia rate and perinatal infant mortality of three groups declined following along with the postponement of pathogenic week of gestation, and there was significance in statistics of three groups（P〈0.05）; Cesarean section was a main method of pregnancy termination for all groups. Conclusion The early-onset severe preeclampsia badly influences the matemal and neonatal outcome. Taking expectant treatment actively and postponing week of gestation properly contribute to improve maternal and neonatal outcome, and cesarean section is the first choice.