同种异体冻干骨加自体骨移植治疗骨缺损

Cryopreserved Dried Bone Together with Bone of Autografts in the Treatment of Bone Defect

目的：报道采用同种异体冻干骨和自体骨混合一起移植治疗骨质缺损的治疗结果．方法：自１９９５年～２０００年对２０例大块骨质缺损因自体骨源不足而采用同种异体冻干骨和自体骨按一定比例混合一起进行植骨修复．年龄９岁～６５岁，平均３２．３岁．骨缺损范围３０ｃｍ３－９０ｃｍ３．随访１年～５年，平均１年７个月．结果：术后平均５．５个月移植骨和宿主骨骨性愈合．３月～６个月功能恢复正常，无不良反应．结论：对治疗大块骨质缺损，应用同种异体冻干骨和自体骨按一定比例混合一起进行植骨治疗是一种有效的方法，可得到类似于自体骨移植的治疗效果．

To discuss the curative effect of treatment bone defect with cryopreserved dried bone and bone of autografts. Methods: 20 cases of massive bone defects of limbs were treated with cryopreserved dried bone together with bone of autografts for short of bone autografts from 1995-2000. Their ages were ranged from 9-65 year-old with an average of 32.3 year-old. The bone defects were from 30-90cm3 in volume. These cases were followed up from 1-5 years (average 19 months). Results: The allografts were integrated with the host bone in 5.5 months on an average and the excellent function of the joint was restored in 3-6 months postoperatively. No adverse effect was found. Conclusions: Application of transplantation of cryopreserved dried bone allografts together with bone of autograft could be an effective method for the treatment massive bone defects. The clinical curative results could be similar to that of transplantation of bone autografts.