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脑通在重型颅脑损伤患者认知障碍中的应用 被引量:5

The effect of nicergoline on cognitive dysfunction in the severe traumatic brain injury
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摘要 目的 :探讨脑通对重型颅脑损伤恢复期患者认知障碍的治疗作用及其机理。方法 :将 52例重型颅脑损伤恢复期患者分为常规治疗组和脑通治疗组 ,治疗前后检测SPECT并评估认知功能 ,分析脑局部血流量及认知功能的变化。结果 :脑通组与常规组治疗后SPECT检查显示病灶数均有明显减少 ,但两者比较无统计学差异。脑通组治疗后认知功能评分较常规组高 ,虽然总体评分无统计学差异 ,但脑通组定向力及记忆力改善优于常规组 (P <0 0 5)。结论 Objective:To explore the therapeutic effect and mechanism of nicergoline on the severe traumatic brain injury. Methods:52 TBI patients were divided into the routine treatment group and nicergoline treatment group. Before and after rehabilitation treatment the SPECT and cognitive function were assessed. Results:The lesions were both decreased in nicergoline group and routine group in SPECT scanning, but there was no difference in statistics. The value of cognitive function of the nicergoline treatment group, especially function-oriented and memory, was higher than that of the routine treatment group( P <0.05). Conclusions:The nicergoline can improve cognitive function of the severe traumatic brain injury.
出处 《中国康复理论与实践》 CSCD 2000年第4期153-155,共3页 Chinese Journal of Rehabilitation Theory and Practice
关键词 脑通 颅脑损伤 认知 SPECT 应用 nicergoline traumatic brain injury cognitive function radionuclide imaging tomography emission computed single phot
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参考文献6

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