摘要
建立了高效液相色谱法测定盐酸米安色林片含量及其有关物质.采用Diamonsil C18色谱柱,以甲醇∶水(35∶65)为流动相,检测波长279 nm.盐酸米安色林在6.0~90.0 μg/ml范围内线性关系良好,回收率为99.8%,RSD为0.53%.
An HPLC method was established for the determination of content and its related substances of mianserin hydrochloride tablets.A Diamonsil C18 column was used with the mobile phase of methanol ∶ water (35 ∶ 65) at the detection wavelength of 279 nm.It was linear in the concentration range of 6.0-90.0 μg/ml.The average recovery was 99.8 %,with RSD of 0.53 %.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2014年第6期570-572,共3页
Chinese Journal of Pharmaceuticals