颅内静脉窦血栓形成的临床及影像学诊断25例报道

Clinical features and radiology for diagnoses of dural venous sinus thrombosis

目的 研究颅内静脉窦血栓形成的病因、临床特点、特别是影像学的表现。方法 回顾性分析25例已确诊的静脉窦血栓形成患者(男 2例，女23例)的临床资料及影像学特点，包括发病原因、临床表现、实验室检查及影像学头部CT、磁共振成像( MRI)和磁共振血管成像(MRA)的异常表现。结果 25例本病患者除2例男性外，余23例均有明确病因，如妊娠期、产褥期、口服避孕药等，临床表现以亚急性颅压高症状为主；部分头部CT可见条索征及空三角征， MRI特征性表现为T1、T2加权像窦内异常高信号， MRA示栓塞的静脉窦未显影。结论 颅内静脉窦血栓形成患者多可找到明确病因，临床表现多样，无特异性，MRI/MRA 可帮助确诊。

Objective To study the etiology, clinical f eatures and particular radiology of dural venous sinus thrombosis (DVST). Methods 25cases (2 males,23 females) of DVST were retrospectiv ely reviewed, including etiology, clinical features, laboratory examinations and CT,MR imaging(MRI) and/or MR angiography of the venous sinuses. Resu lts Except for the two males, all 23 females had definite causes, su ch as during pregnant or puerperium, or taking oral contraceptives.Clinical feat ures included subacute intracranial hypertension, and so on. The CT of some pati ents showed cord signs and △ sign. The MRI with T1/T2 weighted showed hi gh intensity signals inside the thrombosed sinuses. MRA showed loss of plane signal s of thrombosed sinuses. Conclusion Most of patients with DVST have definite causes and various clinical features and can be diagnosed wi th MRI and MRA.