短暂性脑缺血发作的认知功能研究

Study on cognitive function in patients with transient ischemic attack

目的 探讨短暂性脑缺血发作 (TIA)患者的认知功能特点 ,为临床诊断提供依据。方法 用龚氏修订的韦氏成人智力量表 (WAIS -RC)、龚氏修订的韦氏记忆量表 (WMS -RC)及认知功能筛选试验(CCSE)对 39例TIA患者和 39例年龄、性别和教育程度相匹配的正常人进行测试。结果 TIA组智能和记忆障碍发生率分别为 2 3 1%、 5 3 8% ,均高于对照组。WAIS -RC、WMS -RC、CCSE总量表分均显著低于对照组。认知功能损害较全面。结论 TIA患者存在不同程度的认知功能障碍 ;认知功能障碍的早期发现对TIA的诊断有重要价值。

Objective To investigate the change of cognitive function in patients with transient ischemic attack(TIA),and provide bases for clinical diagnosis.Methods 39 patients with TIA and 39 controls,who matched in age ,sex and education,had been tested with WAIS-RC,WMS-RC,CCSE.Results The rates of disturbance of intelligence and memory in patients with TIA were respectively 23 1% and 53 8%,both of them were higher than those in controlled group.The scores of WAIS-RC,WMS-RC,CCSE were all significantly lower than those of controlled group,and cognitive function was generally damaged.Conclusion Patients with TIA may have cognitive function impairment in some degrees and early findings of cognitive function impairment are of great value to diagnosis of TIA.