摘要
本文主要探讨制备用于包虫抗原DNA检测的n型多孔硅微腔生物传感器的可能性.高参杂n型硅片在HF酸/乙醇电解液中实现了具有良好性能的生物传感器基底的制备.通过检测多孔硅微腔浸入不同浓度的生物溶液前后的微腔反射谱的移动量来验证传感器的性能,溶液浓度从0.625μM至10.000μM,检测灵敏度为4.740nm/μM.当微腔基底浸泡0.625μM生物溶液后,微腔红移5nm表明制备的生物传感器是成功的.根据浓度与微腔红移量之间的线性关系表明在多孔硅传感器上检测包虫病的可行性.
The work in this paper has concentrated on fabrication possibility of biosensor for hydatid antigen DNA based on porous silicon microcavities. The substates have been fabricated from highly doped n-type silicon based on HF/ethanol electrolyte system. Examined the reflectance spectra before, after expore to different concentration of echinococcosis ranging from 0.625 μM to 10.000 μM, a detection sensitivity of 4.740 nm/μM has been demonstrated. A redshift of 5nm when the sample was exposed to 0.625 μM hydatid DNA solution. The linear relationship indicates that a potential and significate detection of echinococcosis.
出处
《新疆大学学报（自然科学版）》
CAS
2014年第2期190-193,共4页
Journal of Xinjiang University(Natural Science Edition)
基金
The National Science Foundation of China(61265009 and 11264038)
the Research Foundation for the Doctoral Program ofChinese universities(20116501110003)
the Xinjiang Science and Technology Project(201291109)
关键词
多孔硅
包虫病
微腔
生物传感器
反射光谱
porous silicon
echinococcosis
microcavity
biosensor
reflectance spectrum
