艾滋病感染者手术的麻醉观察

Clinical observation of anesthesia in patients with HIV

目的观察全身麻醉在艾滋病感染者手术中的安全性与可行性。方法选取22例实施全身麻醉的艾滋病感染者,通过对麻醉诱导期、维持期、拔管期的相关指标观察,与同期实施全身麻醉的22例非艾滋病感染者的麻醉效果进行比较。结果麻醉诱导期丙泊酚、舒芬太尼和顺式阿曲库铵的用药量按每公斤体重计算,维持期的用药量则按公斤体重时间计算,两组的丙泊酚、舒芬太尼和顺式阿曲库铵的用药量比较差异均无统计学意义(P>0.05),麻醉过程中血管活性药物使用率(观察组2例,对照组3例)和拔管时间[观察组(15.54±4.24)min,对照组(15.00±4.08)min]比较差异均无统计学意义(P>0.05)。结论艾滋病患者在无症状期接受外科手术时,其对全身麻醉的耐受力与普通患者并无差异,艾滋病感染患者对全身麻醉的耐受性与其是否合并其他合并症和艾滋病发展的程度有关,与是否感染艾滋病病毒无关。

Objective To observe the safety and feasibility of general anesthesia in patients with HIV. Methods Twenty-two patients with HIV undergoing general anesthesia were enrolled （AIDS group, the observa-tion group）. Indicators were recorded at the induction, the maintenance and the extubation of anesthesia. The anes-thetic effect was compared with 22 patients with non-AIDS at the same period （non-AIDS group, the control group）. Results There was no significant difference in the dosage of propofol, sufentanil cis-atracurium between the two groups during induction of anesthesia period （per kilogram of body weight,/kg） and the maintenance period [/（kg＆#183;h）], P〉0.05. There was also no significant difference between the two groups in the vasoactive drugs used during anesthe-sia （2 patients in the observation group and 3 cases in the control group） and the extubation time [（15.54±4.24） min in the observation group and （15.00 ± 4.08） min in the control group], P〉0.05. Conclusion Compared with non-AIDS patients, there was no significant difference in the tolerance of general anesthesia in patients with HIV in the aymptom-atic period. The tolerance of general anesthesia in patients with HIV is related to the other complications and the de-gree of AIDS, regardless of HIV infection.