康复新液抗实验性胃溃疡作用的研究

Study on Action of kangfuxin Solution on Experimental Gastric ulcer

目的 :研究康复新液抗实验性胃溃疡的作用。方法 :采用大鼠幽门结扎胃溃疡模型 ,大鼠醋酸烧灼的胃溃疡型 ,及大鼠无水乙醇胃粘膜损伤型。结果 :表明康复新液对大鼠幽门结扎型及乙醇型胃溃疡模型有明显的保护作用 ,但对醋酸烧灼法引起的胃溃疡模型无保护作用。康复新液还有降低胃酸和胃蛋白酶排出量的作用。结论 :该制剂用于治疗胃及十二指肠溃疡。

Objective: To study the action of kangfuxin solution on the experimental gastric ulcer.Methods: The rat gastric ulcer models induced by the ligated pylorus and burned acetic acid, the gastric moucosa injury model induced by the absolute ethyl alcohol were used.Results: Kanfuxin solution possessed the protective action on the rat gastric ulcer model induced by the ligated pylorus and rat gastic mucosa injury model induced by the absolute ethyl alcohol, but didn't affect the rat gastric ulcer model induced by burned acetic acid. Conclusion: Kangfuxin Solution also has the actions of inhibiting the output of gastric acid and pepsin.