双氯芬酸钾凝胶含量的HPLC测定

Determination of Diclofenac Potassium Gel by HPLC

建立了双氯芬酸钾凝胶含量的 HPL C测定法。采用 YWG- C1 8柱 ,以甲醇 - 5 %醋酸水溶液为流动相 ,检测波长2 75 nm。方法平均回收率为 99.5 5 % ,RSD为 1.2 2 %。

Diclofenac potassium gel was determined by HPLC, using YWG C 18 column, with methanol 5% acetic acid solution (80∶20) as the mobile phase at the detection wavelength of 275 nm. The average recovery was 99.55%, with RSD of 1.22%.