中西医结合治疗慢性肾衰竭的临床观察

Clinical observation of Integrated Traditional Chinese and Western Medicine Therapy on chronic renal failure

目的 :观察中西医结合治疗慢性肾衰竭 (CRF)的疗效。方法 :将 6 8例CRF患者随机分为中西医结合治疗组 (A组 )和西医对照组 (B组 ) ,各为 34例。两组均给优质低蛋白饮食 (LPD)、控制血压、潘生丁、静滴河山胸腺肽 2 0～ 30mg/d ,维持水、电解质及酸碱平衡。尿毒症给强骨生血口服液、α -骨化醇及丙酸睾丸酮。A组静滴参麦注射液 2 0～ 30ml/d ,并服肾衰I号汤剂。B组静滴能量合剂。均以 30d为 1个疗程。分别检测两组治疗前、后BUN、Cr及观察临床表现的变化。结果 :治疗后A组BUN、Cr均显著下降 (P <0 .0 5 ) ,B组BUN均无下降 (P >0 .0 5 ) ,且有上升趋势。以BUN为参照 ,A组与B组总有效率各为 70 %和 2 0 .6 % ;以Cr为参照 ,A组与B组总有效率各为 73.4%和2 0 .6 %。BUN、Cr同步下降 30 %以上 ,A组与B组各为 10例 (2 9.4% )和 1例 (2 .9% )。A组疗效显著优于B组 (P <0 .0 1)。结论 :中西医结合治疗CRF的疗效显著优于西医治疗。

Objective: To observe the effect of Integrated Traditional Chinese and Western Medicine (TCM-WM) therapy on chronic renal failure (CRF).Methods:Sixty-eight patient with CRF were divided randomly into TCM-WM treatment group (AG) and WM controlling group(BG),each is 34 cases.Two groups were given a good low protein diet(LPD)、controlling blood pressure、persantin、vein drip Heshang Thymosin(20～30 mg/d),sustain balance of water、electrolyte and acid-alkal.Uremia were given QianggushengXue Oral Liquid,Alfaclcidol and Testosterone Propionate.In AG were dripped Shengmai Injection(20～30 ml/d) by vein, that is used in renal failure No. I Decoction.BG were dripped energy mixture. One course was 30 days. The changes of blood ureanitrogen(BUN)、Creatinine (Cr)、clinical face before and after treatment were determinated each other in two groups.Results: BUN、Cr in A group were both significantly reduced after treatment (P<0.05), BUN、Cr in BG were both no reduced(P>0.05),But they tend to raise. As compared with BUN, The total effective rate in AG and BG were 70%and 20.6%; As compared with Cr, that were 73.4% and 20.6%.BUN、Cr were both reduced over 30%, AG and BG were 10 cases (29.4%) and 1 case (2.9%). The effect of AG is very marked better than that in BG (P<0.01). Conclusions: The curative effect of TCM-WM therapy on CRF was very marked better than that of WM.