改良背驮式肝移植3例报告

A Report of Three Cases of Improving Piggback Orthotopic Liver Transplantation

目的 总结、探讨改良背驮式肝移植术的临床应用。方法 对 3例肝脏终末期病变 ,行改良的背驮式肝移植术 ,即保留肝后下腔静脉的全病肝切除 ;将供肝植于受肝原位 :供、受体肝上下腔静脉 ,供、受体门静脉 ,供、受肝动脉行对端吻合 ;结扎供肝肝下下腔静脉。用FK 5 0 6、晓悉和泼尼松三联免疫抑制剂抗排斥反应。加强术后监护和感染的控制。结果 病例 1,2目前分别存活 8,5月余 ,生活自理 ;例 3因术后并发急性肾功能衰竭死亡 ,存活 14d。结论 改良背驮式肝移植是治疗肝脏终末期病变的可靠方法。

Objective To study the clinical application of piggyback orthotopic liver transplantation.Method After resection of the patient's liver in preservationof the recipient inferior vena cava, the donor liver was transplanted into the patient with an end to end anastomosis of uphepatic inferior vena cava, portal vein, hepatic artery between the donor and the recipient liver with the ligation of subhepatic inferior vena cava. The liver rejection was controlled by FK 506、 Xiaoxi and Predison. We monitored the patient and prevent him from infection after the operation. Result At present the two patients have normally survived for 8、5 months respectively. The thired patient dired of renal failure. Conclusions The liver transplantation is a safe and effective curable means of end-stage liver disease.