磁共振扩散加权成像在脑梗死超急性期诊断中的应用

Applicaton of DWI in diagnosis of hyperacute cerebral infarction

目的：探讨磁共振扩散加权成像在急性脑梗死诊断中的应用价值。方法回顾性分析脑梗死患者60例的临床资料，根据磁共振检查距发病时分为＜6h组，6h～组，24h～组，48～72h组，选取病灶中心以及对应的检测部位5×5像素大小区域，测定器ADC值，计算rADC值。结果不同时间点组内健侧和患侧ADC值比较存在显著差异（P＜0.01），患侧显著低于健侧。组间ADC值以及rADC值比较差异无统计学意义（P＞0.05）。结论 DWI脑梗死超急性期就能显示出清晰异常信号，对脑梗死超急性期的诊断具有显著临床意义。

Objective To discuss applicaton of DWI in diagnosis of hyperacute cerebral infarction. Methods Clinical data of 60 cases with hyperacute cerebral infarction were retrospectively analyzed. All cases were divided into 〈 6h group,6h- group, 24h- group and 48-72h group according to time of MRI detection. ADC was detected and rADC was counted at selected lesion center and the corresponding detection part 5×5 pixel size area. Results ADC of uninjured side and injured side in different time had significant difference（P〈0.01）, which of injured side was lower. ADC and rADC showed no significant difference in different groups（P 〉 0.05）. Conclusion DWI can show clear abnormal signal in hyperacute cerebral infarction, and show clinical significance in diagnosis of hyperacute cerebral infarction.