能谱CT对良、恶性甲状腺结节的鉴别价值

Evaluation of spectral CT in differentiating benign and malignant thyroid nodules

目的评价能谱CT鉴别甲状腺良、恶性结节的能力。方法入组58例甲状腺结节患者,共72个甲状腺结节,分成良性结节及恶性结节组。用能谱CT对其进行平扫及动脉期增强扫描,分别得到平扫和增强后结节的ICnod(碘浓度)及NICnod(标准化碘浓度)值,并比较其在良、恶性组间的差别。结果平扫时恶性结节的ICnod、NICnod值明显低于良性组(P<0.001),其诊断恶性结节的敏感度及特异度分别为100%到92.3%和89.1%到87%。增强后良、恶性组结节的ICnod、NICnod值没有统计学差异。结论能谱CT平扫可以帮助鉴别甲状腺良、恶性结节。

Objective To evaluate the performance of spectral CT parameters to distinguish benign and malignant thyroid nodules .Methods A total of 58 patients with 72 nodules underwent plain and arterial phase enhancement spectral CT scan and were divided into benign and malignant groups .ICnod ,NICnod in plain and enhancement scan were derived .All the parameters were compared among the groups .Results The parameters ICnod and NICnod in plain scan for the malignant group were significantly lower than benign group （ P〈0 .001） .The sensitivities and specificities for the parameters were from 100% to 92 .3% and from 89 .1% to 87% .ICnod ,NICnod in enhancement scan had no significant difference .Con-clusion The spectral CT in plain scan could differentiate benign and malignant thyroid nodules .