卵巢癌起源及发病机制研究的最新进展

The progress of the origin and pathogenesis of ovarian cancer

卵巢癌起源及发病机制的研究近年来出现了很多新的理论,包括卵巢癌不是一个单独的疾病,而是可以根据形态学和分子遗传学差异进行两级分类的一组疾病。卵巢癌均起源于卵巢外,其中浆液性癌来源于输卵管伞,子宫内膜样和透明细胞癌来源于经输卵管逆流的子宫内膜形成的异位病灶,粘液性和Brenner瘤起源于输卵管与卵巢间皮之间的Walthard细胞巢。本文就对此取得的一些最新的研究进展进行综述报道。

Many new theories in the study of the origin and the pathogenesis of ovarian cancer were proposed in recent years, such as ovarian cancer is not a single disease, but is a group of diseases classified according to the differences in morphology and molecular genetics. Ovarian cancers all come from outside the ovary, serous carcinoma originates from fimbria tubaria, endometrioid carcinoma and clear cell carcinoma originate from the endometriosis uterine focus through fallopian tube reflow, mucous and Brenner tumor originate from the Walthard cell nests between fallopian tubes and ovaries mesothelium.