不同年龄组健康老人10年肺功能随访

Follow-up study of lung function for 10 years in health elder of differential age

目的：探讨不同年龄组健康老年人10年肺功能变化及各项肺功能指标改变具体数值。方法：经体检、胸片、心电图、肺功能等多项检查后确定为健康老年人作为研究对象；每年均进行查体及肺功能的随访。结果：第一秒用力呼气量占用力肺活量（FEV1%）在 60-64 岁组、65-69 岁组的初始值和 10 年后测量值相比未达到统计学意义，70 岁以上组的健康老年人 FEV1% 初始值与 10 年后测量值相比下降P<0.05。呼气峰流速（PEF）、肺总量（TLC）在 60-64 岁组初始值和 10 年后测量值相比P<0.05；在 65-69 岁组及 70 岁以上组 PEF、TLC 的初始值和 10 年后测量值相比P<0.01。肺活量（VC）、用力肺活量（FVC）、第一秒用力呼气量（FEV1）、最大通气量（MVV）、最大呼气中期流量（MMEF）、功能残气量（FRC）、残气量（RV）、RV/TLC 各年龄组初始值与 10 年后随访值相比P<0.01。VC、FVC、FEV1、PEF、RV、RV/TLC、FEV1%、MVV、MMEF、FRC、TLC 年改变值在各年龄组比较变化不显著。结论：肺功能随增龄而改变；绝大多数肺功能指标 10 年前、后对比变化差别极显著P<0.01; FEV1% 在 60-64 岁、65-69 岁年龄组 10 年前、后改变P>0.05,在 70 岁以上年龄组P<0.05; PEF、TLC 在 60-64 岁年龄组 10 年前、后改变P<0.05;

Objective:To study the changes and the data of lung functions in the health elder of differential age.Methods:The lung functions were follow up by the time after physical examination, chest x ray,electrocardiogram. Results: The forced expiratory volume in 1 second/Forceal vital capacity(FEV1%) of inital data compared with FEV1% of data after 10 years are no statistics satisfactory in the 60－64 age and 65－69 age. FEV1% of initial data compared with FEV1% of data after 10 years is P<0.05 in the over 70 age old.Peak expiratory flow(PEF)、total lung capacity (TLC) of initial data compared with PEF, TLC of data after 10 years are P<0.05, in the 60-64 age old;P<0.01in the 65-69 age old and over 70 age old. Vital capacity (VC), forced vital capacity (FVC), the forced expiratory volume in 1second(FEV1),maximal voluntary ventilation(MVV), maximal mid-expiratory flow curue(MMEF),functional resideal capacity(FRC),residual volume(RV),RV/TLC of initial data companed with these of data after 10 years are P<0.01 in the differential age group VC、FVC、FEV1、FEV1%、PEF、MVV、MMEF、FRC、TLC、RV、RV/TLC of every year change data are P>0.05 in the differential age Conclusions: The lung functions change with in crease of age; FEV1%,PEF,TLC is more distinctly; data of changes of every year is no statistics satisfactory in the differential age group