摘要
采用表面涂覆硅烷偶联剂KH550、两步光接枝、阳极氧化等方法,在钛表面成功制备出一种pH型敏感膜覆盖的载银二氧化钛(TiO2)纳米管阵列。利用扫描电镜(SEM)、透射电镜(TEM)、能谱分析(EDS)、原子吸收光谱(AAS)对该pH敏感膜覆盖的载银TiO2纳米管阵列理化性能进行了表征,采用抑菌环实验定性考察了样品的抗菌特性,并计算其抑菌率。结果表明,含银离子溶液在毛细管力作用下大量进入TiO2纳米管中,并在pH型敏感膜的调控下,使银离子在不同pH环境下具备不同的释放行为,从而达到良好的控释效果;载银TiO2纳米管的抑菌率与银离子负载量成正比,且抗菌性能持久。
Ag-loaded TiO2 nanotube covered by a pH-sensitive membrane were prepared by coating a silane coupling agent KH550 accompanied with a two-step photo-grafting and anodization,and its physicochemical properties were characterized by means of SEM,TEM,EDS and AES.Also,the antibacterial activities of these samples were accessed by inhibition zone and inhibition rate.The results suggest that,the solution containing Ag ions enters into the interior of TiO2 nanotubes under the interactions of capillary force,and the release behavior of Ag ions is regulated and controlled by the pH-sensitive polymer membrane at different pH environment.Also,it is found that the antibacterial ratio of Ag-carried nanotubes is proportional to the carrying content of Ag ions.
出处
《无机化学学报》
SCIE
CAS
CSCD
北大核心
2014年第6期1299-1304,共6页
Chinese Journal of Inorganic Chemistry
基金
国家重大科学研究计划(2012CB933902)资助项目
关键词
钛种植体
二氧化钛纳米管
银离子
pH敏感膜
智能控释
抗菌性能
titanium implant
TiO2 nanotubes
Ag ions
pH-sensitive membrane
intelligent controlled release
antibacterial activity
