甲状腺微血管计数及其临床意义

THE COUNT AND CLINICAL SIGNIFICANCE OF MICROVESSEL IN THYRIOD CARCINOMAS

目的 了解甲状腺癌微血管量与肿瘤转移预后的关系。方法 应用第Ⅷ因子相关抗原 ,通过免疫组化方法检测 45例甲状腺癌组织中微血管数。结果 甲状腺癌组织学分化差、伴有转移者 ,其微血管数高于分化好、无转移者。结论 甲状腺癌组织中微血管数与其组织学特征密切相关 ,微血管数高的易发生转移 ,且预后不良。

Objective To investigate the relationship between microvessel count in thyroid carcinomas and metastasis and prognosis. Methods The microvessel count in thyroid carcinomas of 45 cases was studied by the immunochemistric technique using anti-Ⅷ related antigen. Results Microvessel count in undifferentiaed and those with metastasis carcinomas was higher than that in well-differentiated and those without metastasis. Conclusion Microvessel count in thyroid carcinoma correlates well with the histologic characteristic of carcinoma. High microvessel count of thyroid carcinoma predicts a bad prognosis and metastasis at high risk.