住院2型糖尿病合并抑郁症患者生命质量的相关性研究

Analysis on the quality of life in type 2 diabetes accompanying with depression in hospitalized patients

目的通过研究住院2型糖尿病合并抑郁症患者生存质量变化,探讨住院糖尿病患者生存质量影响及其相关影响因素。方法 2型糖尿病患者146例,以抑郁自评量表(Self-rating depression scale,SDS)进行自我抑郁评分,根据SDS测定结果分为研究组(SDS≥50分)57例;对照组(SDS<50)89例。采用糖尿病病人特异性生存质量量表(Diabetes Specific Quality of Life Scale,DSQL)测定两组患者的生存质量。调查患者一般情况及并发症、血糖控制情况等。结果研究组较对照组生存质量总分、各维度因子分明显升高,差异有统计学意义。锻炼的次数、血糖监测与DSQL呈正相关,SDS、体质指数(Body Mass Index,BMI)、并发症的数目与DSQL呈负相关,与婚姻状况、家族遗传史有相关性,而与性别、年龄、文化程度、抽烟、饮酒无相关性。结论婚姻状况、锻炼、遗传史、SDS、BMI、血糖监测、并发症是影响2型糖尿病患者生存质量的重要因素。抑郁症可导致糖尿病患者生存质量下降。保持积极乐观的心态,加强锻炼,控制体重,经常监测血糖,减少并发症的发生,有利于个性指标的控制,从而能够改善糖尿病患者的生命质量,促进患者康复。

Objective To observe the changes of the quality of life in type 2 diabetes accompanying with depression in hospitalized patients, and to explore the relationship between diabetes mellitus and depression. Methods 146 patients with type 2 diabetes were examined with Special of Quality of Life for Diabetes Mellitus （DSQL） and Self-reporting Depression Scale （SDS） , then these patients were divided into the case group （SDS ≥50）（ n = 57 ） and the control group （ SDS 〈 50） （ n = 89 ）. The patients with general information, complications and blood sugar control were observed in the two groups. Results The scores of DSQL and all factors in case group showed obvious increase when compared with control group;DSQL showed positive associations with the number of exercise and blood glucose monitoring, but negative association with SDS, BMI and the number of complications. DSQL was also correlated with marital status, family history of disease, but had no association with gender, age, culture degree, smoking and drinking. Conclusions The main influencing factors on DSQL of type 2 diabetes are marital status, exercise, the genetic history, SDS, BMI, blood glucose monitoring and complications. Depression can cause the decline of quality of life in patients with diabetes mellitus. Maintaining a positive and optimistic attitude, positive exercise, weight control, regular monitoring of blood sugar can reduce the incidence of complications and control individual index, so as to improve the quality of life of patients with diabetes, and promote rehabilitation of patients.