性行为与乙型肝炎及丙型肝炎病毒感染的关系

Relationship between Sexual Behavior and Infection of Hepatitis B and Hepatitis C Virus

目的 评估高危性行为人群中乙型肝炎病毒 (HBV)及丙型肝炎病毒 (HCV)的感染情况及某些高危性行为与HBV、HCV感染的关系。方法 用PCR方法对本院性传播疾病 (STD)门诊中的 173名就诊者进行HBV、HCV检测 ,并对被调查者的年龄、初次性生活年龄、3个月内性侣数、终身性侣数、性生活方式、既往STD史等作调查。既往有吸毒史及受血史者不纳入调查范围。结果 HCV感染在有高危性行为的人群中尤其在STD人群中常见 ,并与既往STD史呈正相关。 3个月内性侣数超过 4个是HBV、HCV感染的危险因素。HBV、HCV感染在梅毒患者中最多见。结论 HBV。

Purpose: To evaluate HBV and HCV infection among high risk sexual behavior group and the relationship between them. Methods: 173 cases were investigated at the STD outpatient departnent of Huashan Hospital. The questionarie measured sexual risk factors including age, the number of lifetime sex partners, the number of sex partners in recent three months, the age of first intercourse, the history of STD, the style of sexual behavior. HBV-DNA and HCV-RNA were detected by PCR. Patients who had past history of drug abuse or blood transfusion were excluded. Results: HCV positive rate was higher in high risk group, especially in STD patients, and was positively related with STD history. Having sexual intercourse more than four partners in the last three months is the risk factor in getting HBV or HCV infection HBV and HCV infection are most commonly seen in syphilis people. Conclusions: HCV infection is more oftenly seen among STD patients and people with multiple sex partners. Thus the sexual behavior way may play an important role in the transmission of HBV and HCV.