一种新型水溶性甲壳胺衍生物的制备及结构确证

Preparation and charactarisition of a new type water soluble chitosan derivative

水不溶性甲壳胺 (DAC- 85)与葡萄糖、半乳糖、乳糖等在酸性条件下生成希夫碱型衍生物 ,然后在硼氰化钠的作用发生还原烷基化反应 ,生成了含有糖支链的水溶性甲壳胺衍生物。利用 1HNMR及 13

Reaction of chitosan with glucose, galactose and lactose was performed in lactic acid MeOH to give corresponding schiff's base derivatives, the following reduction was carried out in the presence of sodium cyanoborohydride to prepare branched chain water soluble chitosan derivatives. The structure of derivatives were Confirmed by 1 HNMR and 13 CNMR.