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2型糖尿病胰岛素治疗方案的选择 被引量：6

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摘要 糖尿病目前是一个高患病率的慢性疾病,严重危害人类的健康.流行病研究显示2010年全球成年患者约2.85亿（6.4％）,2030年将达到4.39亿（7.7％）^[1].其中我国20岁以上糖尿病患者为9240万（9.7％）,已经成为全球糖尿病患者最多的国家,其中2型糖尿病（T2DM）患者占绝大多数^[2].研究发现T2DM患者发病时胰岛细胞功能仅剩50％,并且随着糖尿病病程的延长而进行性下降^[3]（图1）.
作者 李伟 肖新华
机构地区 北京协和医学院中国医学科学院北京协和医院内分泌科卫生部内分泌重点实验室
出处 《中华糖尿病杂志》 CAS CSCD 2014年第5期281-284,共4页 CHINESE JOURNAL OF DIABETES MELLITUS
关键词 2型糖尿病 治疗方案 胰岛素 成年患者 胰岛细胞功能 糖尿病病程 慢性疾病 T2DM
分类号 R587.1 [医药卫生—内分泌]
  • 相关文献

参考文献24

  • 1Shaw JE, Sieree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030[ J ]. Diabetes Res Clin Praet,2010, 87 : 4-14.
  • 2Yang W, Lu J, Weng J,el al. Prevanlence of diabetes among men and women in China[J]. N Engl J Med,2010,362:1090-1101.
  • 3Kendall DM, Cuddihy RM, Bergenstal RM. Clinical application of ineretin-based therapy: therapeutic potenlial, patienl selection, and clinical use[J]. Am J Med, 2009, 122(6 Suppl) :S37-50.
  • 4Weng J, I,i Y, Xu W, el al. Effect of intensive insulin therapy on [3-cell fimction and glycaemic control in patients with newly diagnosed type :2 diabetes: a multicentre randomised parallel-grouptfialEJ. Lancet, 2008,371:1753-1760.
  • 5UK Prospective Diabetes Study (UKPDS) Group. Intensive blood- glucose control with sulphonylureas or insulincompared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) [J]. Lancet, 1998, 352: 837-853.
  • 6UK Prospective Diabetes Study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes( UKPDS 34) [ J]. Lancet, 1998,352 : 854-865.
  • 7Garber AJ, Abrahamson MJ, Barzilay JI, et al. American Association of Clinical Endocrinologists' comprehensive diabetes management algorithm 2013 consensus statement-executive summary[ J ]. Endoer Pract,2013 ,19 :536-557.
  • 8Chaitman BR, Hardison RM, Adler D, et al. The Bypass Angioplasty Revascularization Investigation 2 Diabetes randomized trial of different trealment strategies in type 2 diabetes mellitus with stable ischemic heart disease : impact of treatment strategy on cardiac mortality and myocardial infarction [ J ]. Circulation,2009, 120:2529-2540.
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二级参考文献33

  • 1Kirstine Brown Frandsen.糖尿病治疗管理的现状[J].国外医学（内分泌学分册）,2005,25(3):172-173. 被引量：28
  • 2潘长玉,中国区合作调查组.中国糖尿病控制现状——指南与实践的差距 亚洲糖尿病治疗现状调查1998,2001及2003年中国区结果介绍[J].国外医学（内分泌学分册）,2005,25(3):174-178. 被引量：396
  • 3张巧,胡颖,双倩.心理性胰岛素抵抗的相关因素分析[J].临床荟萃,2005,20(19):1111-1112. 被引量：8
  • 4Hu D,Xie J,Fu P,et al.Central rather than overall obesity is related to diabetes in the Chinese population:.the InterASIA study.Obesity (Silver Spring),2007,15:2809-2816.
  • 5Pan C,Yang W,Jia W,et al.Management of Chinese patients with type 2 diabetes,1998-2006:the Diabcare-China surveys.Curr Med Res Opin,2009,25:39-45.
  • 6Raskin P,Allen E,Hollander P,et al.Initiating insulin therapy in type 2 diabetes:a comparison of biphasic and basal insulin analogs.Diabetes Care,2005,28:260-265.
  • 7Yang W,Ji Q,Zhu D,et al.Biphasic insulin aspart 30 three times daily is more effective than a twice-daily regimen,without increasing hypoglycemia,in Chinese subjects with type 2 diabetes inadequately controlled on oral antidiabetes drugs.Diabetes Care,2008,31:852-856.
  • 8Concato J,Shah N,Horwitz RI.Randomized,controlled trials,observational studies,and the hierarchy of research designs.N Engl J Med,2000,342:1887-1892.
  • 9Korytkowski M. When oral agents fail: pratical barriers to starting insulin. International Journal of Obesity, 2002, 26: S18-S24.
  • 10Peyrot M. Resistance to insulin therapy among patients and providers: results of the cross national Diabetes Attitudes, Wishes, and Needs (DAWN) study. Diabetes Care, 2005, 28: 2673-2679.

共引文献216

同被引文献47

  • 1郑雪枫,刘晓蓉.门冬胰岛素联合甘精胰岛素与胰岛素泵强化治疗2型糖尿病的疗效对比[J].医学信息（医学与计算机应用）,2014,0(1):74-74. 被引量：3
  • 2马建华,李倩,李惠琴,李冬梅,陶小军,刘好,张颖,吴锦丹,毛晓明.甘精胰岛素与胰岛素泵的基础胰岛素剂量比较[J].医学研究生学报,2006,19(11):1004-1005. 被引量：4
  • 3中华医学会糖尿病学分会.中国2型糖尿病防治指南(2010年版)[J].中华糖尿病杂志,2010,2增刊2:1-56.
  • 4Shaw J E, Sicree R A, Zimmet P Z.Global estimates of theprevalence of diabetes for 2010 and 2030[J].Diabetes Res Clin Pract, 2010, 87(2): 4-14.
  • 5Yang W, Lu J, Weng J, et al.Prevanlence of diabetes among men and women in China[J].N Engl J Med, 2010, 362(3): 1090-1101.
  • 6Kendall D M, Cuddihy R M, Bergenstal R M.Clinieal application of ineretin-based therapy: therapeutic: potential, patient selection, and clinical use[J].Am J Med, 2009, 122(6 Suppl): S37-50.
  • 7Weng J, Li Y, Xu W, et al.Effeet of intensive insulin therapy on 3-cell function and glycaemic control in patients with newlydiagnosed type 2 diabetes: a multieentrerandomised parallel-group trial[J]. Lancet, 2008, 371(1): 1753-1760.
  • 8Garber A J, Abrahamson M J, Barzilayj I, et al.AmericanAssociation of Clinical Endocrinologists comprehensive diabetesmanagement algorithm 2013 consensus statementexecutivesummaryl[J].Endocr Pract, 2013, 47(19): 536-557.
  • 9Hooqwerf B J.Prioperative management of diabetes mellitius; how shouldwe act on the limited evdence[J].Cleve Clin J Med, 2006, 73(Suppl 1): 95-99.
  • 10Garber AJ, Abrahamson MJ,Barzilayj I,et al.American Associ- ation of Clinical Endocrinologists comprehensive diabetes manage- ment algorithm 2013 consensus statement executive summaryl[J]. Endocr Pract,2013,47(19):536-557.

引证文献6

二级引证文献32

中华糖尿病杂志
2014年 第5期

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