某院2012年住院患者头孢菌素类药物使用频度的分析

Analysis of DDDs of Cephalosporins of Inpatients in A Hospital During 2012

目的:分析太仓市第一人民医院住院患者头孢菌素类药物的使用情况。方法:利用医院HIS系统软件,检索2012年度住院药房头孢菌素类药物的出库数量、金额;以限定日剂量(DDD)、用药频度(DDDs)、药物利用指数(DUI)等为指标分析2012年度住院患者头孢菌素类药物使用情况。结果:2012年住院患者使用头孢菌素类药物有27种,占总抗菌药物金额的58.03%,其中,第3代头孢菌素类药物是临床治疗的主导药物。结论:2012年住院患者使用头孢菌素类药物属基本合理,但有些过量使用,有导致耐药菌产生和增加不良反应的可能,应严格掌握用药指征。

Objective： To analyse the use of cephalosporins of inpatients in the No.1 People＇s Hospital of Taicang. Methods： Retrieving the amount of cephalosporins out of inpatient dispensary in 2012 using hospital＇s HIS software. Analysing the use of cephalosporins of inpatients in 2012 using the indexes of defined daily dose（DDD）,daily defined doses（DDDs） and drug utilization index（DUI）. Results： There were 27 kinds of cephalosporins used by the inpatients in 2012,which accounted for 58.03% of antibacterial drugs. The third generation cephalosporins were the dominant drugs during clinical treatments. Conclusion： The use of cephalosporins of inpatients was basically reasonable in 2012,but some were overused. It may generate the drug-resistant bacteria and increase the possibility of adverse reactions. The drug use must be strictly controlled.