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急性心肌梗死后急性肾损伤的发生率和病死率的KDIGO和RIFLE标准比较 被引量:3

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摘要 目的急性肾损伤(AKI)增加急性心肌梗死(AMI)的死亡危险,改善全球肾病预后(KDIGO)组织提出新的AKI定义。本研究的目的在于比较AMI住院患者前7d内应用RIFLE+KDIGO标准诊断AKI的早期和晚期病死率。,方法1100例AMI患者纳入本研究。结果根据RIFLE和KDIGO标准,确定为AKl分别为14.8%和36.6%。采用多变量Cox分析,AKI与增加30d的病死率校正风险比(AHR)有关,RIFLE标准为3.51(95%C12.35~5.25,P〈0.001),KDIGO为3.99(95%c,2.59~6.15,P〈0.001);1年的死亡AHRRIFLE和KDIGO分别为1.84(95%C,1.12~3.01,P=0.016)和2.43(95%C,1.62—3.62,P:0.001)。RIFLE确定为非AKI而KDI-GO确定为AKI的亚组患者亦增加30d病死率的AHR2.55(95%c,1.52—4.28)和1年病死率的AHR2.28(95%叫1.46~3.54,P=0.001)。结论对于AMI患者来说,KDIGO较RIFLE标准能够检出更多的AKI患者,KDIGO确定的AKI而RIFLE未确定为AKI的患者早期和晚期病死率亦明显增高。本研究显示KDIGO更适合于AMI患者AKI的确定。
作者 石江顺
出处 《中国实用医刊》 2014年第13期89-91,共3页 Chinese Journal of Practical Medicine
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参考文献12

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同被引文献19

  • 1吴海云,赵玉生,许强,朱姝.早期发生急性肾衰竭与急性心肌梗死后心源性休克患者预后的关系[J].中华老年多器官疾病杂志,2004,3(2):110-112. 被引量:7
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