妊娠中晚期阴道菌群与妊娠结局的相关性研究

The Relationship between Vaginal Microflora in the Third-trimester and the Outcomes of Pregnancy

目的:观察妊娠中晚人群中,阴道菌群分布情况与妊娠结局的关系。方法:纳入我院2012年1月至2012年12月收治的28-35周的妊娠中晚期患者。依据阴道菌群情况分为正常组和异常组。比较两组患者的妊娠结局情况。结果:异常组菌群分布为滴虫7例(8.75%),假丝酵母菌51例(63.75%),衣原体11例(13.75%),淋菌2例(2.50%),细菌性阴道病9例(11.25%)。异常组在不良妊娠结局以及新生儿情况显著高于正常组(P<0.05)。而且异常组中,有症状的患者不良妊娠结局以及新生儿情况显著高于无症状患者(P<0.05)。结论:妊娠中晚期阴道菌群以假丝酵母菌感染最多,可明显增加胎膜早破,新生儿感染,产褥感染的概率。

Objective：To observe the pregnancy middle-late crowd, vaginal flora distribution and the relationship between the pregnancy outcome , and observe the trial-produce success and the thickness of the lower uterine segment cesarean delivery woman .Method： In our hospital from January 2012 to December 2012 , 28-35 weeks of pregnancy middle-late patients .On the basis of vaginal flora the pregnancy was divid-ed into normal group and abnormal group .Compare two groups of patients with pregnancy outcome .Result：The abnormal group flora distribution trichomonad 7 cases （8.75）, candida 51 cases （63.75）, chlamydia in 11 cases （13.75）, gonococcus in 2 cases （2.50）, 9 cases of bacterial vaginal disease （11.25）.Abnormal groups in adverse pregnancy outcomes and neonates was significantly higher than that of normal group （ P 〈0.05） .And abnormal group , adverse pregnancy outcomes in patients with symptoms and neonates was signif-icantly higher than that of asymptomatic patients （ P 〈0.05） .Conclusion： Pregnancy middle-late vaginal flora with candida yeast infection most , premature rupture of membranes can obviously increase , neonatal in-fection, and the probability of puerperal infection .