透析中递增式抗阻运动改善维持性血液透析(MHD)患者的心肺耐力、心理状态和健康相关生活质量

Intradialytic progressive resistance training improved cardio-respiratory endurance, psychological state, and health-related quality of life in maintenance hemodialysis patients

目的探讨透析中递增式抗阻运动对维持性血液透析(maintenance hemodialysis,MHD)患者心肺耐力、心理状态和健康相关生活质量的影响。方法入选本透析中心的MHD患者,应用Bruce方案平板运动测定最大摄氧量(peak oxygen uptake,VO2peak)及代谢当量(metablic equivalents,METs)等,完成焦虑(Self-Rating Anxiety Scale,SAS)和抑郁评分(Self-Rating Depression Scale,SDS),应用生活质量评分简表(Short Form-36,SF-36)评估生活质量。所有入组患者完成12周透析中递增式抗阻运动,运动结束后再次评价上述指标,比较其前后结果有无统计学差异。结果抗阻运动后MHD患者的VO2peak升高了57.93%(P<0.01),METs提高56.77%(P<0.01);SAS评分下降8.60%(P<0.05),SDS评分降低20.19%(P<0.01);SF-36评分中的生理机能、一般健康状态及精力评分分别提高了47.83%、72.58%及47.37%(P<0.05)。结论透析中递增式抗阻运动可明显改善MHD患者的心肺耐力、心理状态和部分健康相关生活质量评分。

Objectives To explore the effects of intradialytic progressive resistance training on cardio-respiratory endurance,psychological state,and health-related quality of life in maintenance hemodialysis （MHD） patients.Methods The MHD patients in this study were recruited from our dialysis center.At the baseline and after the intradialytic progressive resistance training for 12 weeks,peak oxygen uptake （VO2max） and metabolic equivalents （METs） using treadmill exercise of Bruce sport program were measured.In addition,self-rating anxiety scale （SAS）,self-rating depression scale （SDS）,and health-related quality of life （short form-36 health survey,SF-36） were completed.We then compared these parameters and statistically analyzed the data before and after the resistance training.Results After the intradialytic progressive resistance training,VO2peak increased by 57.93％ （P＜0.01）,METs increase by 56.77％ （P＜0.01）,SAS score decreased by 8.60％ （P＜ 0.05）,SDS score decreased by 20.19％ （P＜0.01）,SF-36 scores for physical function,general health and vitality increased by 47.83％,72.58％ and 47.37％,respectively （P＜0.05）.Conclusion Intradialytic progressive resistance training significantly improved cardio-respiratory endurance,psychological state,and health-related quality of life in MHD patients.