卡前列素氨丁三醇联合低位B-Lynch缝合术治疗前置胎盘剖宫产产后出血

The Effect of Carboprost Tromethamine Combined with Low B-Lynch Suture in the Treatment of Postpartum Hemorrhage after Cesarean Delivery for Placenta Previa

目的探讨卡前列素氨丁三醇联合低位B-Lynch缝合术治疗前置胎盘剖宫产产后出血的疗效。方法将2012年7月—2013年10月64例前置胎盘患者随机分为两组,实验组32例,在剖宫产术中采用卡前列素氨丁三醇联合低位B-Lynch缝合术对胎盘剥离面进行止血;对照组32例,在剖宫产术中采用缩宫素联合传统的"8"字缝合方法对胎盘剥离面进行止血。比较两组术中出血量、术后24 h内出血量、手术时间、子宫切除率。结果①两组手术时间比较,实验组较对照组手术时间明显缩短,差异有统计学意义(P<0.05)。②术中出血量相比较,实验组比对照组显著减少,差异有统计学意义(P<0.05)。③术后24 h内出血量相比,差异有统计学意义(P<0.05)。④两组子宫切除率相比较,实验组无一例切除子宫,对照组有3例切除子宫,差异无统计学意义(P>0.05)。结论卡前列素氨丁三醇联合低位B-Lynch缝合术是治疗前置胎盘剖宫产术中胎盘剥离面出血的有效方法。

Objective To explore the effect of carboprost tromethamine combined with low B-Lynch suture in controlling postpar-tum hemorrhage after cesarean delivery for placenta previa. Methods 64 cases of patients with placenta previa from July, 2012 to October, 2013 were randomly divided into two groups. For controlling postpartum hemorrhage in the surface of placental separa-tion, 32 patients in the experimental group were given carboprost tromethamine combined with low B-Lynch suture, 32 cases in the control group were given oxytocin combined with traditional ＆#39;8＆#39; suture method. The blood loss volume during the operation and within 24 hours after operation, the operation time and the rate of hysterectomy of two groups were compared. Results ①The oper-ation time of the experimental group was significantly shorter than that of the control group, the difference was statistically signifi-cant （P〈0.05）. ②The blood loss volume during operation of the experimental group was significantly less than that of the control group, the difference was statistically significant （P〈0.05）.③Compared the blood loss volume within 24 hours after operation, there was a statistically significant difference between the two groups （P〈0.05）. ④Compared the rate of hysterectomy, the experimental group had no case of hysterectomy, the control group has 3 cases, the difference was not statistically significant （ P〉0.05）. Conclu-sion Carboprost tromethamine combined with low B-Lynch suture is effective to control postpartum hemorrhage in cesarean deliv-ery for placenta previa.