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急性冠脉综合征患者血清IL-8、hs-CRP及ox-LDL的变化 被引量：6

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摘要 急性冠状动脉综合征（acute coronary syndrome, ACS）是一组由急性心肌缺血引起的临床综合征, 包括急性心肌梗死（acute myocardial infarction, AMI）及不稳定型心绞痛（unstable angina pectoris, UAP）, 冠状动脉内斑块的破裂而导致血栓形成是ACS的主要原因[1]。其早期的诊断及对疾病的严重程度的了解对于临床有效的治疗起着积极的作用。本实验通过对ACS患者定量检测血清IL-8, 高敏C反应蛋白（high-sensitive C-reactive protein, hs-CRP）及氧化低密度脂蛋白（oxidized low density lipoprotein, ox-LDL）水平, 探讨其与ACS的关系。
作者 许静莉 张继军
机构地区 西安文理学院卫生所 西安医学院附属医院
出处 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2014年第8期861-862,共2页 Chinese Journal of Cellular and Molecular Immunology
关键词 急性冠脉综合征 白细胞介素8 高敏C反应蛋白 氧化低密度脂蛋白
分类号 R392.11 [医药卫生—免疫学] R543.3 [医药卫生—心血管疾病]
  • 相关文献

参考文献20

  • 1Libby P. Inflammation in atherosclerosis [ J ]. Nature, 2002, 420(6917) : 868 -874.
  • 2Galkina E, Ley K. and inflamnatory mechanisms of atherosclemsis [J]. Annu Rev Immunol, 2009, 27:165 -197.
  • 3Pang ZJ. Effect of polysaccharide Krestin on the up-regulation of macrophage colony-stimulating factor gene expression in protecting mouse peritoneal macrophages from oxidative injury[ J]. Am J Chin Med, 2003, 31(1) : 11 -23.
  • 4FmstegNd J. Inrmnity, athemsclemsis and cardiovascular disease[ J/OL ]. BMC Med, 2013, 11: 117.
  • 5Yang H, Mohamed AS, Zhou SH. Oxidized low density lipoprotein, stem ceils, and atherosclerosis [ J/OL ]. Lipids Health Dis, 2012, 11: 85.
  • 6Matsuura E, Kobayashi K, Tabuchi M, et al. Oxidative modification of low density lipoprotein and immune regulation of atherosclerosis [J]. Prog Lipid Res, 2006, 45(6) : 466 -486.
  • 7MeisingeT C, Baumert J, Khuseyinova N, et al. Plasma o:ddized low-density lipoprotein, a strong predictor for acute coronary heart disease events in apparently healthy, middle-aged men from the general population [J]. Circulation, 2005, 112(5): 651 -657.
  • 8Bla1enberg S, Rnpprecht HI, Bickel C, et al. Glutathione per-oxidase 1 activity and cardiovascular events in patients with coronary artery disease[J]. N Engl J Med, 2003, 349(17) : 1605 -1613.
  • 9Basati G, Pourfamam M, Movahedian A, et al. Reduced plasrm adiponectinlevels relative to oxidized low density lipoprotein and nitric oxide in coronary artery disease patients [ J ]. Clinics ( Sao Paulo), 2011, 66(7) : 1129 -1135.
  • 10高阅春,李全,何继强,姜腾勇,任学军,陈方.超敏C反应蛋白水平与冠心病严重程度及预后的相关性研究[J].中国全科医学,2012,15(8):840-843. 被引量：119

二级参考文献18

  • 1Libby P,Ridker PM. Inflammation and atherosclerosis:role of C-reactive protein in risk assessment[J].American Journal of Medicine,2004.9-16.
  • 2Koenig W,Sund M,Frohlich M. C-reactive protein,a sensitive marker of inflammation,predicts future risk of coronary heart disease in initially healthy middle-aged men:results from the MONICA (monitoring trends and determinants in cardiovascular disease) Augsburg Cohort Study 1984 to 1992[J].Circulation,1999,(02):237-242.doi:10.1161/01.CIR.99.2.237.
  • 3Zebrack JS,Muhlestein JB,Horne BD. C-reactive protein and angiographic coronary artery disease:independent and additive predictors of risk in subjects with angina[J].Journal of the American College of Cardiology,2002,(04):632-637.doi:10.1016/S0735-1097(01)01804-6.
  • 4Scirica BM,Morrow DA,Cannon CP. Clinical application of C-reactive protein across the spectrum of acute coronary syndromes[J].Clinical Chemistry,2007,(10):1800-1807.doi:10.1373/clinchem.2007.087957.
  • 5Avanzas P,Arroyo-Espliguero R,Cosin-Sales J. Markers of inflammation and multiple complex stenoses (pancoronary plaque vulnerability) in patients with non-ST segment elevation acute coronary syndromes[J].Heart,2004,(08):847-852.
  • 6Lu L,Pu LJ,Xu XW. Association of serum levels of glycated albumin,C-reactive protein and tumor necrosis factor-α with the severity of coronary artery disease and renal impairment in patients with type 2 diabetes mellitus[J].Clinical Biochemistry,2007,(11):810-816.doi:10.1016/j.clinbiochem.2007.03.022.
  • 7Cushman M,Arnold AM,Psaty BM. C-reactive protein and the 10-year incidence of coronary heart disease in older men and women:the cardiovascular health study[J].Circulation,2005,(01):25-31.doi:10.1161/CIRCULATIONAHA.104.504159.
  • 8Pearson TA,Mensah GA,Alexander RW. Markers of inflammation and cardiovascular disease:application to clinical and public health practice:a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association[J].Circulation,2003,(03):499-511.doi:10.1161/01.CIR.0000052939.59093.45.
  • 9Kosuge M,Ebina T,Hibi K. Value of serial C-reactive protein measurements in non ST-segment elevation acute coronary syndromes[J].Clinical Cardiology,2008,(09):437-442.doi:10.1002/clc.20267.
  • 10Boekholdt SM,Hack CE,Sandhu MS. C-reactive protein levels and coronary artery disease incidence and mortality in apparently healthy men and women:the EPIC-Norfolk prospective population study 1993-2003[J].Atheroclerosis,2006,(02):415-422.doi:10.1016/j.atherosclerosis.2005.09.023.

共引文献118

同被引文献40

引证文献6

二级引证文献37

细胞与分子免疫学杂志
2014年 第8期

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