老年人髋部骨折围术期静脉补铁的作用

Effect of perioperative intravenous iron sucrose therapy in elderly patients with hip fractures

目的探讨老年人髋部骨折围术期静脉补充蔗糖铁降低手术输血率的作用。方法收治200例65岁及以上的髋部骨折并行手术治疗的患者。补蔗糖铁组（100例）接受静脉补蔗糖铁（600mg，静脉滴注），对照组（100例）未接受蔗糖铁。评估两组患者术后输血率、感染率、死亡率及住院天数等指标。结果老年人髋部骨折围术期静脉补蔗糖铁组的输血率（25．0％）低于未接受蔗糖铁组（41．0％）（P〈0．05）；两组患者感染率、死亡率及住院天数等指标的比较差异无统计学意义（P〉0．05）。结论老年髋部骨折围术期静脉补充蔗糖铁可以降低临床输血率。

Objective To evaluate the effect of perioperative intravenous （IV） iron sucrose therapy on reducing postsurgical blood transfusion rates in elderly patients with hip fractures. Methods From September 2011 to February 2014, 200 patients aged≥65 years with hip fractures were enrolled. The iron sucrose group （n= 100） received iron sucrose （600 mg, IV）, while the control group （n= 100） did not receive iron sucrose. Postsurgical blood transfusion rates, infection rates, mortality and length of hospital stay were evaluated. Results The difference in blood transfusion rates was significant （ 25.0% vs. 41.0 %, P〈0.05）, while differences in infection rates, mortality and length of hospital stay were not significant between the two groups. Conclusions Perioperative IV iron sucrose can reduce blood transfusion requirements in elderly patients with hip fractures.