摘要
目的 探讨尿微量白蛋白（urine microalbuminuria,U-ALB）、纤维蛋白原（fibrinogen,Fb）、血红蛋白（hemoglobin,Hb）在2型糖尿病视网膜病变中的临床意义.方法 临床病例对照研究.对2010年4月至2012年12月在沧州眼科医院住院的141例2型糖尿病患者,分为无视网膜病变组80例（A组）、合并视网膜病变组61例（B组）;正常对照组60名;均进行尿U-ALB和血浆Fb及Hb检测.结果 U-ALB在B组较A组增加,差异有统计学意义（F =1080.507,P＜0.05）.Fb在A、B组较正常对照组均升高,且B组更高,差异有统计学意义（F =130.399,P＜0.05）.Hb在A、B组较正常对照组均降低,且B组降低更明显,差异有统计学意义（F =163.085,P＜0.05）.结论 U-ALB、Fb、Hb水平变化与糖尿病及糖尿病视网膜病变发生密切相关.
Objective To evaluate urine microalbuminuria （U-ALB）,fibrinogen （Fb）,hemoglobin （Hb） in type 2 diabetic retinopathy and to analyze the clinical significance.Methods Clinical case studies.From April 2010 to December 2012 in Cangzhou ophthalmology hospital,141 patients with type 2 diabetes were divided into the group of 80 patients without retinopathy diabetic retinopathy group of 61 patients,60 normal controls.U-ALB,Fb and Hb were detected in all the cases.Results U-ALB in group B was higher than group A,the difference was statistically significant （F =1080.507,P 〈0.05）.Fb in the group A and B were higher than normal control group,which was the highest in group B,the difference was statistically significant （F =130.399,P 〈0.05）.Hb in the group A and B were lower than the normal control group,and the group B decreased more significantly,the difference was statistically significant （F =163.085,P 〈0.05）.Conclusions The changes of U-ALB,Fb,Hb are closely related with diabetes and diabetic retinopathy.
出处
《中国实用眼科杂志》
CSCD
北大核心
2014年第6期698-700,共3页
Chinese Journal of Practical Ophthalmology
