Fcγ受体在胎盘细胞的分布

Distribution of Fc γ receptor in human placenta

目的 检测 Fcγ受体 (Fcγ R)在胎盘组织的分布 .方法 免疫荧光染色法结合普通荧光显微镜观察 .结果 人胎盘滋养层细胞表面存在 Fcγ R ,主要分布于滋养层细胞和绒毛间质细胞 .Fcγ R 主要存在于绒毛间质细胞 .Fcγ R 在胎盘的各层细胞均未检测到 .另外 ,这 3型 Fcγ R在绒毛间隙的母血细胞中也存在 .结论 Fcγ R 分布在不同的胎盘细胞 ,提示可能与其不同功能有关 .

AIM To detect the distribution of Fc γ R in human placenta. METHODS Immunofluorescent technology and fluorescence microscopy were used. RESULTS HBsAg seropositive and seronegative placenta tissues were tested for Fc γ R by immunofluorescent technology. We found that Fc γ RⅢ was mainly expressed on trophoblast cells (TC) and villous meseachymed cells (VMC), Fc γ RⅡ only on VMCs and Fc γ RⅠ was not found on any placenta cells. In addition, all three types of Fc γ R existed in inter villous space of mother bloodstream. CONCLUSION Three types of Fc γ R were found in different placenta cells, which suggests they may be in correlation with their functions.