瘢痕疙瘩术后联合^(90)Sr/^(90)Y敷贴疗效观察

Observation of the Effect of the Postoperative Joint ^(90)Sr/^(90)Y Radiotherapy in Keloid

目的:观察瘢痕疙瘩手术切除后早期联合90Sr/90Y敷贴治疗与单用90Sr/90Y敷贴治疗的疗效比较。方法:56例瘢痕疙瘩患者行手术切除后早期联合90Sr/90Y敷贴治疗(A组),60例瘢痕疙瘩患者行单纯90Sr/90Y敷贴治疗(B组),治疗结束后所有患者随访观察1年,比较其临床疗效。结果:A组56例患者均治疗有效,总有效率为100%,其中痊愈47例,总治愈率为83.9%;B组60例患者均治疗有效,总有效率为100%,其中痊愈50例,总治愈率为83.3%。两组总有效率、治愈率比较差异均无统计学意义(P>0.05)。A组治疗疗程较B组短,不良反应较B组少,差异均有统计学意义(P<0.05)。结论:手术切除早期联合90Sr/90Y敷贴治疗瘢痕疙瘩疗程短、安全、不良反应较少、临床效果令人满意。

Objective：To observe the effect of postoperative joint 90Sr/90Y radiotherapy in keloid.Method：90Sr/90Y contact therapy was given to 56 cases after surgery（group A）. 90Sr/90Y radiotherapy was given to 60 cases（group B）. All patients were followed up for 1year after combined therapy,and the clinical effects of the two groups were compared. Result：47 cases in the group A were cured,the total cure rate was 83.9%,total effective rate was 100%. 50 cases in the group B were cured,the total cure rate was 83.3%,total effective rate was 100%. The total effective rate,cure rate of the two groups were compared,the differences had no statistical significance（P〉0.05）. The period of treatment in the group A was shorter than that of the group B,the adverse reaction was less than that of the group B,the differences had statistical significance（P〈0.05）.Conclusion：Early operation resection combined with 90Sr/90Y application in the treatment of keloid has a short course of treatment,less adverse reaction,safe,satisfactory clinical effect.