协同刺激分子与自身免疫性甲状腺病
摘要
协同刺激分子是免疫系统B细胞和T细胞活化以及T、B细胞间相互作用的重要调节因子。协同刺激分子特别是CD40 /CD40L间的反应过度是导致自身免疫性甲状腺病 (AITD)发生的一个重要因素。抗CD40L治疗有望成为治疗该病的有效新途径。
出处
《国外医学（内分泌学分册）》
2001年第2期70-73,共4页
Foreign Medical Sciences(Section of Endocrinology)
参考文献10
-
1Smith T J,Sempowski G D,Berenson C S,et al.Human thyroid fibroblasts exhibit a distinctive phenotype in culture:characteristic ganglioside profile and functional CD40 expression[].The Journal of Endocrinology.1997
-
2Metcalfe R A,Mcintosh R S,Berg F M,et al.Detection of CD40 on human thyroid follicular cells: analysis of expression and function[].The Journal of Clinical Endocrinology.1998
-
3Kyburz D,Corr M,Brinson D C,et al.Human rheumatoid factor production is dependent on CD40 signaling and autoantigen[].J Immunol.1999
-
4Faure G C,Lejzerowicz D B,Bene M C,et al.Rapid communication coexpression of CD40 and class Ⅱ antigen HLA-DR in Graves disease thyroid epithelial cells[].Clinical Immunology and Immunopathology.1997
-
5Kooten C V,Banchereau J.CD40-CD40 ligand[].Journal of Leukocyte Biology.2000
-
6Datta S K,Kalled S L.CD40-CD40 ligand interaction in autoimmune disease[].Arthritis and Rheumatism.1997
-
7Grewal L S,Flavell R A.CD40 and CD154 in cell-mediated immunity[].Annual Review of Immunology.1998
-
8Yellin M,Brett J,Baum D,et al.Functional interactions of T cells with endothelial cells: the role of CD40-CD40L-mediated signal[].The Journal of Experimental Medicine.1995
-
9Griggs N D,Agersborg S S,Ledbetter J A,et al.The relative contribution of the CD28 and gp39 costimulatory pathways in the clonal expansion and pathogenic acquisition of selfreactive T cells[].The Journal of Experimental Medicine.1996
-
10Cao H J,Wang H S,Zhang Y,et al.Activation of human orbital fibroblasts through CD40 engagement result in a dramatic induction of hyaluronan synthesis and prostaglandin endoperoxide H synthase-2 expression[].Journal of Biological Chemistry.1998
-
1邹阳春.内皮细胞白细胞间相互作用与心肌缺血再灌注损伤[J].中国心血管杂志,1998,3(2):127-129.
-
2洪伟,陈铁镇.脂质过氧化对内皮细胞和单核细胞间相互作用的影响[J].中国医科大学学报,1994,23(2):88-92.
-
3孙水林,钟恢海,席文娜.肾综合征出血热相关细胞因子研究进展[J].中华实验和临床感染病杂志（电子版）,2007,1(4):243-245. 被引量：2
-
4施健,谢渭芬.自身免疫性肝病的发病机制[J].中华肝脏病杂志,2005,13(1):49-50. 被引量：16
-
5赵晋晋,雷闽湘.浅谈高糖高脂环境下肾小球内皮细胞与系膜细胞间相互作用对细胞外基质产生的影响[J].求医问药（下半月刊）,2011,9(6):24-25.
-
6黄循铷,王承党,王瑞幸,焦海霞.溃疡性结肠炎小鼠肠道通透性改变与TNF-α及NF-κB P65的关系[J].中国应用生理学杂志,2016,32(2):112-115. 被引量：36
-
7孙玉芬.36例支气管哮喘病的护理体会[J].新医学导刊,2008,7(10):30-31.
-
8丁洋.多种多样的过敏原和过敏反应[J].家庭医学（下半月）,2011(4):10-11.
-
9韩冰,韩凌.细胞间相互作用和糖尿病视网膜病变[J].实用糖尿病杂志,2005,13(1):48-50.
-
10王东信.脓毒症病理生理的研究进展[J].国外医学（麻醉学与复苏分册）,2005,26(5):264-267.
