叶酸治疗高半胱氨酸血症30例临床观察

Clinical Observation of Folic Acid to Homocysteine Disease

为观察叶酸治疗同型半胱氨酸血症的效果及不良反应 ,选择冠心病中高同型半胱氨酸血症患者 30例 ,采用自身前后对照方法 ,每日服叶酸 0 .8mg。结果 :服药 2周后有 53.3% ( 1 6/30 )的病人同型半胱氨酸浓度降至正常 ,4周时 93.3% ( 2 8/30 )的病人降至正常 ,用药过程中无不良反应。结果提示 :口服叶酸能有效降低同型半胱氨酸浓度。

WT5BZ]To observe the effects and side effects of folic acid to plasma homocysteine disease, 30 coronary patients with high plasma homocysteine were selected. They took 0.8 mg folic acid per day and their homocysteine levels were compared before and after being treated. The homocysteine levels of 53.3 % patients decreased to normal by taking folic acid for two weeks. The homocysteine levels of 93.3 % patients decreased to normal by taking folic acid for four weeks. No side effect was found.Conclusion: The homocysteine levels can be effectively decreased by taking folic acid for four weeks.