红景天与乙酰唑胺改善高原脑—体功效能力的对比研究

Effect of Rhodiola and Acetazolamide in Improving Hypoxia in High Altitude

目的 :筛选并证实在高原低氧环境中能改善人体工作能力的有效药物。方法 :随机选择海拔370 0m某施工部队健康青年 2 4名 ,分组各 12人 ,自愿分别服用报道对人体有改善代谢作用的红景天胶囊和乙酰唑胺片剂 ,服药前后均进行 2 4h睡眠剥夺及同等负荷的自行车功量运动 ,采用DDX -2 0 0型电脑多功能心理生理测试仪进行视觉注意分配 ,左右脚交叉动作频率的对比测验。结果 :服用红景天和乙酰唑胺后视觉注意分配和左右脚交叉动作频率操作的总次数、正确次数显著增多 (p <0 0 1或p <0 0 5 )。错误次数显著减少 (p <0 0 1)。结论 :口服红景天或乙酰唑胺均能显著改善和提高高原移居者脑—体工作能力 ,红景天作用稍优于乙酰唑胺。

Objective: To study the effects of rhodiola and acetazolamide on hypoxia with high altitude Method: 24 healthy soldiers living and working at a plateau 3700 m above sea level were divided into two groups: rhodiola group (12 cases) and acetazolamide group (12 cases) The two drugs were administrated orally DDX-200 multifunction psychological machine were used to do psychological tests (vision division test and left/right feet cross exercise) under the stress of sleep deprivation (24 hours) and physical exercise, before and after drug administration respectively Result: After drug administration, the total count, rate of correct performance in vision division and left/right feet cross tests were increased significantly (p<0 01 and p<0 05 respectively), while the rate of false performance in the above two tests decreased markedly (p<0 01) Conclusion: Rhodiola and Acetazolamide can improve the achievements in psychological tests under stress in high altitude area