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大肠癌患者血清p53抗体检测的临床意义 被引量：1

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作者 曹立宇 欧玉荣 张洪福
机构地区 安徽医科大学病理教研室
出处 《实用癌症杂志》 2001年第2期207-207,210,共2页 The Practical Journal of Cancer
基金 安徽省卫生厅基金资助!(A95 1 998 2 3)
关键词 大肠肿瘤 P53抗体 免疫组织化学 大肠癌
分类号 R735.34 [医药卫生—肿瘤]
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参考文献5

  • 1[1]Sinicrope FA,Ruan SB,Cleary KR,et al. bcl-2 and p53 oncoprotein expression during colorectal tumorigenesis [J]. Cancer Res, 1995,35(2) :237.
  • 2[2]Ohue M,Tomita N,Monden T,et al. A frequent alteration of p53gene in carcinoma in adenoma of colon[J ]. Cancer Res, 1994, 54 (17) :4798.
  • 3[3]Schlichtholz B,Legros Y,Gillet D,et al. The immune response to p53 in breast cancer patients is directed against immunodominant epitopes unrelated to the mutational hot spot [J]. Cancer Res, 1992,52(22) :6380.
  • 4[4]Hammel P,Boissier B,Chaumette MT,et al. Detection and monitoring of serum p53 antibodies in patients with colorectal cancer[J]. Gut, 1997,40(3) :356.
  • 5[5]Angelopoulou K,Diamandis EP, Sutherland DJ, et al. Prevalence of serum antibodies against the p53 tumor suppressor gene protein in various cancer [J]. Int J Cancer, 1994,58 (4): 480.

同被引文献19

  • 1Crawford LV, Pim DC, Bulbrook R,et al.Detection of antibodies against the cellular protein p53 in sera from patients with breast cancer[J].Int J Cancer,1982,30(2):403-408.
  • 2Linzer DI, Levine AJ. Characterization of a 54K Dalton Cellular SV 40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells[J]. Cell,1979,17(1):43-52.
  • 3Wunderlich H, Hindermann W, Huller M, et al. The correlation of p53 protein overexpression and p53 antibodies in serum of patients with transitional cell carcinoma of the urinary bladder[J]. Urol Int,2000,64(3):13-17.
  • 4Kanaya N, Okuda M, Toyama N,et al. Detection of the anti-bodies in dogs with tumors[J]. J Vet Med Sci,2002,64(11):973-979.
  • 5Sakai H, Okamoto E. Clinical importance of serum anti-p53 antibodies as tumor markers[J]. Rinsho Byori,2002,50(10):970-975.
  • 6Hammel P, Leroy-Viard K,Chaumette MT,et al. Correlations between p53-protein accumulation ,serum antibodies and gene mutation in colorectal cancer[J]. Int J Cancer,1999,81(5):712-718.
  • 7Guinee DG Jr,Travis WD, Travis GE,et al.Gender comparisonsin human lung cancer: analysis of p53 mutations,anti-p53 serum antibodies and C-erbB-2 expression[J].Carcinogenesis,1995,16(5):993-1002.
  • 8Andrew M, Davidoff J,Dirk Igjehart, et al.Immune response to p53 is dependent upon p53/hsp70 complexes in breast cancers [J].Autoimmunity,1999,89(6):3439-3442.
  • 9Herkel J,Modrow JP, Bamberger S, et al.Prevalence of auto-antibodies to the p53 protein in auto-immune hepatitis[J].Autoimmunity,2002,35(8):493-496.
  • 10Von Brevern MC, Hollstein MC, Cawley HM, et al.Circulating anti-p53 antibodies in esoplageal cancer patients are found predominantly individuals with p53 core domain mutations in their tumors [J]. Cancer Res,1996,56(5):4917-4921.

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实用癌症杂志
2001年 第2期

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