5%鱼藤酮悬浮剂的研制

Preparation of 5% Rotenone SC

[目的]为鱼藤酮悬浮剂的工业化生产提供理论依据。[方法]采用流点法筛选润湿分散剂,探索最优润湿分散剂配方以及粘度调节剂品种和用量,并对产品稳定性指标进行检测。[结果]5%鱼藤酮悬浮剂的配方确定为:5%鱼藤酮、4%分散剂SC3、1%农乳602#、0.1%黄原胶、1%白炭黑、5%乙二醇、0.2%甲醛,去离子水补至100%。该制剂的各项指标均符合水悬浮剂的标准要求。[结论]该制剂低毒低残留,符合无公害用药要求,具有良好的推广前景。

[ Objective ] The research aimed to provide theoretical basis for the industrialized production of rotenone SC. [ Method ] The wetting dispersant was screened out by using flow point method. The best formula of wetting dispersant, the kinds and amount of viscosity modifier were explored. And its stability indices were detected. [ Result ] The formula of 5 % rotenone SC was confirmed as 5 % rotenone ,4% dispersing agent SC3,1% emulsifier 602#,0.1% xanthan gum, 1% silica white,5 % ethylene glycol,0.2% methanal and deionized water （ up to 100% ） All the indices were accordant with the quality standard of SC. [ Conclusion] The prepared rotenone SC was of low toxicity and low residue, which was accordant with the requirements of pollution-free drug administration. Therefore the prepared rotenone SC had good popularization foreground.