热毒宁注射液联合阿奇霉素治疗儿童肺炎支原体肺炎的临床疗效

Clinical efficacy of Reduning injection combined with azithromycin in the treatment of mycoplasmal pneumonia of children

目的探讨热毒宁注射液联合阿奇霉素治疗儿童肺炎支原体肺炎的疗效。方法选取湖北省襄阳市妇幼保健院儿科140例肺炎支原体肺炎患儿，完全随机分为观察组（70例）和对照组（70例）。观察组应用阿奇霉素10mg／（kg·d）加热毒宁注射液10ml静脉滴注，对照组单纯使用阿奇霉素10mg／（kg·d）治疗。2组均治疗5d。治疗5d后观察比较2组临床疗效、退热时间、咳嗽消失时间、平均住院时间的情况。结果观察组总有效率为98．6％（69／70），对照组总有效率为88．6％（62／70），2组比较差异有统计学意义（P〈0．05）。。观察组退热时间、咳嗽消失时间及住院时间均短于对照组[（3．3±1．5）d比（5．0±1．2）d，（4．5±1．2）d比（5．3±1．4）d，（9．8±1．3）d比（12．1±2．0）d]，差异均有统计学意义（均P〈0．05）。结论热毒宁联合阿奇霉素治疗小儿肺炎支原体肺炎，症状消失快，疗效明显。

Objective To study the Clinical efficaey of reduning injection combined with azithromycin in the treatment of mycoplaslnal pneumonia of children. Methods Totally 140 children with myeoplasma pneumonia were divided randomly into observation group （70 cases） and control group （70 cases）. The observation group was treated with azithromycin combined with reduning injection; the control group was given azithromycinlO rag/（ kg · d）. Two groups were treated for 5 days. Clinical efficacy, antifebrile time, cough disappeared time and average length of hospital stay of two groups were observed and compared after treatment of 5 days. Results The efficacy rate was 98.6% （69/70） in observation group and 88.6% （62/70） in control group （ P 〈 0.05 ）. The antifebrile time, cough disappeared time and average length of hospital stay of observation group were shorter than those of control group [（3.3±1.5）dvs （5.0±1.2）d,（4.5±1.2）d vs （5.3±1.4）d, （9.8±1.3）d vs （12.1 ± 2.0） d ] （all P 〈 0.05 ）. Conclusion The combination therapy of reduning injection amt azithromycin （：an improve the symptom of mycoplasmal pneumonia.