分娩方式对乙肝病毒母婴传播的影响

The Impact of Delivery Mode on the Mother-to-child Transmission of Hepatitis B Virus

目的分析探讨分娩方式对乙肝病毒母婴传播的影响。方法选取2011年10月—2013年2月该院的240例HBsAg阳性孕产妇及其新生儿为研究对象,将其根据分别方式分为A组(剖宫产组)120例和B组(阴道顺产组)120例,然后将2组新生儿的HBsAg阳性率、HBV DNA阳性率及抗HBs阳性率进行统计与比较。结果 B组的HBsAg阳性率、HBV DNA阳性率均高于A组,抗HBs阳性率则低于A组,且B组孕产妇中HBsAg阳性和HBsAg、HBeAg阳性者的新生儿HBsAg阳性率、HBV DNA阳性率均高于A组,差异有统计学意义(P<0.05)。结论剖宫产可有效降低乙肝病毒母婴传播,更为适用于此类产妇。

Objective To analyze and investigate the impact of delivery mode on the mother-to-child transmission of hepatitis B virus. Methods 240 HBsAg-positive pregnant women and their newborns admitted in our hospital from October, 2011 to February, 2013 were selected as the subjects, and they were divided into group A（caesarean section group）, 120 cases, and group B（sponta-neous vaginal delivery group）,120 cases. Then the HBsAg positive rate, HBV DNA positive rate and anti-HBs positive rate of the newborns in two groups were counted and compared. Results The HBsAg positive rate and HBV DNA positive rate of group B were both higher than those of group A, anti-HBs positive rate was lower than that of group A, and the HBsAg positive rate of the pregnant women and HBsAg positive rate, HBV DNA positive rate of the HBsAg-positive and HBeAg-positive newborns in group B were higher than those of group A, the differences were statistically significant, all P〈0.05. Conclusion The caesarean section can effectively control the mother-to-child transmission of hepatitis B virus ,so it is more suitable for these pregnant women.