骨外科老年感染患者的病原菌分布及耐药监测研究

The Distribution of Pathogenic Bacteria and Drug Resistance Monitoring of Senile Patients with Infection in Bone Surgery

目的分析骨外科老年感染患者主要病原菌的分布情况及耐药率,为临床抗菌药用药提供参考。方法随机选取该院300例骨科老年患者,从患者的伤口中采集分泌物标本,并对标本进行细菌培养及细菌鉴定,并进行药敏试验。结果在300例患者中,共检出298株细菌,142株格兰阴性菌(47.7%),150株格兰阳性菌(50.3%),6株真菌(2%)。结论医院感染病原菌的耐药性较复杂,构成变化快,应严格按照病原菌耐药性检测及鉴定结果,选择合适的抗生素药物为骨科老年患者进行治疗,降低患者感染率。

Objective To analyze the distribution of main pathogenic bacteria and drug resistance of senile patients with infection in bone surgery so as to provide a reference for clinical use of antibiotic drugs. Methods 300 cases of senile orthopedic patients admitted in our hospital from April, 2011 to April, 2013 were randomly selected. Secretion samples were collected from the wound of the patients for bacteria culture and bacteria identification, and drug sensitive test was conducted. Results Of the 300 cases of patients, a total of 298 strains of bacteria were detected, including 142 strains of gram negative bacteria（47.7%）, 150 strains of gram positive bacteria（50.3%）, 6 strains of fungi（2%）. Conclusion The drug resistance of nosocomial infection pathogens is relatively complex, which changes quickly, so appropriate antibiotic drugs for the treatment of senile orthopedic patients, should be chosen in accordance with the pathogen resistance test and the result of appraisal strictly in order to reduce the infection rate of the patients.