丙戊酸钠与左乙拉西坦应用于小儿癫痫临床分析

Clinical Analysis of Sodium Valproate and Levetiracetam Using in Pediatric Epilepsy

目的:探讨丙戊酸钠与左乙拉西坦在癫痫患儿中的治疗效果。方法:选取2012年1月-2013年10月笔者所在医院收治的80例癫痫患儿,按照治疗方法的不同分为观察组和对照组,各40例。观察组给予丙戊酸钠治疗,对照组给予左乙拉西坦治疗,比较两组的治疗效果。结果:观察组总有效率为82.5%,与对照组的80.0%比较,差异无统计学意义(P>0.05)。两组患儿的不良反应发生率比较差异无统计学意义(P>0.05)。结论:丙戊酸钠与左乙拉西坦均是治疗小儿癫痫的有效药物,两者疗效和不良反应相当,值得临床推广。

Objective： To discuss the therapeutic effect of Sodium Valproatc and Levetiracetam using in pediatric epilepsy. Method： Selection from January 2012 to October 2013 the author＇s hospital treated 80 cases of children with epilepsy, according to the treatment method they were divided into observation group and control group, 40 cases in each.Observation group was given Sodium Valproate treatment, control group was given Levetiracetam treatment, compared two groups of therapeutic effect.Result： Observation group total effective rate was 82.5%, compared with 80.0% in the control group, there was no statistically significant difference（P〉0.05）. Two groups of children with adverse reactions to compare difference had no statistical significance（P〉0.05）.Conclusion： Sodium Valproate and Levetiracetam are all effective dru,,s for nediatric enilensv, the adverse reactions are fairly the same, it is worth for clinical use.