常规疗法联合高压氧治疗脑水肿疗效观察

The Observation of Curative Effect of the Traditional Therapy Combined with Hyperbaric Oxygen Therapy in the Treatment of the Cerebral Edemas

目的:探讨50例车祸伤致脑水肿的患者用高压氧治疗临床效果并分析其治疗机制。方法:收集2010年1月-2013年1月笔者所在医院住院的50例车祸伤致脑水肿患者,按治疗方法不同随机分为常规治疗组和联合治疗组,治疗时间均为10 d,比较两组治疗效果。结果:10 d后按照格拉斯哥预后评分标准(GOS)为预后评分评定,常规治疗组治疗有效率为69.23%,联合治疗组治疗有效率为91.66%,两组比较差异有统计学意义(P<0.05)。结论:脑水肿患者配合高压氧治疗可以减轻脑水肿、降低颅内压,明显改善脑细胞微循环、减少脑组织的坏死范围并加快脑受损部位修复。

Objective：To analyze the clinical results and mechanism of 50 cases of cerebral edema caused by traffic accident in the treatment of hyperbaric oxygen. Method：Fifty cases of cerebral edema caused by traffic accident from January 2010 to January 2013 in the hospital were collected,which were randomly divided into two groups according to the different treatment methods. The first group was the conventional treatment group,the second group was the combined treatment group,the treatment time was 10 days. The clinical effects between two groups were compared after treatment. Result：In accordance with the Glasgow Outcome Scale Standard（GOS） for the prognostic score assessment after 10 days. The effective rate of conventional treatment group was 69.23%,while the combined therapy group was 91.66%,and the difference between the two groups was statistically significant（P〈0.05）. Conclusion：Hyperbaric oxygen therapy can reduce patients with cerebral edema,increase intracranial pressure,improve brain cell microcirculation significantly,reduce the scope of brain tissue necrosis and accelerate repair the damaged parts of the brain.