低分子肝素治疗不稳定型心绞痛56例

The Effect of Fragmin in Treatment of Unstable Angina

目的 :观察低分子肝素 (法安明 )对不稳定型心绞痛的疗效。方法 :10 0例患者随机分为两组。对照组(44例 )给予硝酸异山梨酯、硝苯地平、阿司匹林、复方丹参注射液等常规药物治疗 ;治疗组 (5 6例 )在此基础上加用低分子肝素治疗。结果 :临床症状改善的显效率和总有效率治疗组为 82 .1% ,92 .9% ,对照组为 5 4.5 % ,6 3 .6 %。两组比较差异极显著 (P均 <0 .0 1) ;心电图改善的总有效率分别为 80 .4%和 5 0 .0 % ,差异极显著 (P <0 .0 1)。结论 :低分子肝素治疗不稳定型心绞痛有显著疗效。

Objective:To study the effect of Fragmin in treatment of unstable angina (UA). Methods:100 patients with UA were randomized into treatment group and control group. In the control group, the subjects were given routine drugs such as sorbitrate, nifedipine and aspirin, while those in the treatment group given fragmine in addition to the routine drugs. Results:The response rates in the treatment and control groups were 82.1% and 54.5%, respectively (P<0.01). The total effective rates in the treatment and control groups were 92.9% and 63.6%, respectively (P<0.01). The total effective rate of EKG improvement in the treatment and control groups were 80.4% and 50.0%, respectively (P<0.01). Conclusion: Fragmin is effective in the treatment of UA.