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新的肌肉因子:肌联素 被引量:3

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摘要 肌联素是新发现的肌肉因子,为补体C1q/肿瘤坏死因子相关蛋白家族成员,又叫做补体C1q/肿瘤坏死因子相关蛋白15。机体营养状况、运动训练调节骨骼肌肌联素的mRNA表达和循环中肌联素水平。肌联素可通过内分泌的形式作用于外周脂肪组织和肝脏,上调脂肪酸转运蛋白的表达,促进脂肪酸的摄入,降低血清自由脂肪酸的水平,参与肥胖和胰岛素抵抗的发生,可能成为代谢性疾病防治的新靶点。
作者 曹玉仙 张靓
出处 《生理科学进展》 CAS CSCD 北大核心 2014年第2期115-117,共3页 Progress in Physiological Sciences
基金 国家自然科学基金(81270921)资助课题
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