多糖铁复合物胶囊和硫酸亚铁片治疗缺铁性贫血的疗效比较

The comparison of the efficacy of the polysaccharide iron complex capsules and ferrous sulfate tablets for the treatment of iron-deficiency anemia

目的:观察多糖铁复合物胶囊和硫酸亚铁片治疗缺铁性贫血的临床疗效。方法:选择2012年10月—2013年10月确诊的缺铁性贫血患者190例,随机分为两组,各95例。对照组口服硫酸亚铁片,每次2片,每日3次,治疗组口服多糖铁复合物胶囊,每次2粒,每日1次。治疗16周,观察两组患者治疗前后血常规各项指标变化情况以及临床疗效。结果:两组患者治疗后血常规红细胞指标均有所改善,治疗组与对照组比较差异有统计学意义(P<0.05),白细胞和血小板指标变化比较差异无统计学意义(P>0.05)。治疗组治疗后和对照组治疗后总有效率比较,差异有统计学意义(P<0.05)。结论:口服多糖铁复合物胶囊改善缺铁性贫血的效果优于硫酸亚铁片,是一种安全有效的补铁制剂。

Objective：To observe clinical efficacy of polysaccharide iron complex capsules and ferrous sulfate tablets in the treatment of iron - deficiency anemia. Methods：From October 2012 to October 2013,totally 190 patients with iron - defi-ciency anemia who were diagnosed in our hospital were randomly divided two groups,each of 95 cases. The control group was treated with ferrous sulfate tablets,two tables each time,three times a day,the treatment group was treated with polysaccharide iron complex capsules,two capsules each time,once a day. After 14 weeks,the change of the indicators of blood routine and the clinical efficacy were observed before and after treatment. Results：After treatment,the erythrocyte indicators have improved in two groups,the difference was statistically significant（P 〈 0. 05）,while the changes of white blood cell and platelet indexes were no obvious difference（P 〉 0. 05）;The total efficiency of the treatment group after treatment was significantly differences （P 〈 0. 05）. Conclusion：The effect of polysaecharide iron complex capsules on iron - deficiency anemia was superior to that of ferrous sulfate tablets,it was a safe and effective iron preparation.