气管导管外给药管在全麻神经外科手术中的应用

Application of administration outside of tracheal tubes in general anesthesia neurosurgery

目的 观察“气管导管外给药管”（专利号：201320589265.0）在全麻神经外科手术中预防气管插管和气管拔管应激反应的效果.方法 选择择期行神经外科手术的患者50例,ASA分级Ⅰ～Ⅱ级,随机分为气管导管外给药管组（L组）和对照组（C组）,两组患者均采用经口明视气管插管.插管前,在L组气管导管上装上气管导管外给药管,C组气管导管表面涂上无菌生理盐水,比较两组患者麻醉诱导前、插管后2min、拔管前1分钟、拔管后5min的血压、心率变化及呛咳的发生率.结果 两组患者诱导前的血压、心率无显著差异（P＞0.05）;L组患者气管插管后2min、拔管前1min及拔管后5min的血压、心率变化及呛咳的发生率均低于C组（均P＜0.05）.结论 气管导管外给药管用于神经外科手术,可减轻患者插管后及拔管期心血管反应,减少呛咳的发生.

Objective To investigate the effect of administration outside of tracheal tubes （Patent No.201320589265.0） on prevention endotracheal intubation and extubation cardiovascular reactions in anesthesia in neurosurgery.Methods 50 neurosurgery patients,ASA Ⅰ-Ⅱ,were randomly divided into 2 groups including L group and C group.Before intubation,L group was installed tracheal administration tube and C group tracheal tube coated with sterile saline.The blood pressure,heart rate and incidence cough before induction of anesthesia,intubated after 2min and 1 minute before extubation after extubation of 5mins were observed.Results The blood pressure and heart rate of induce had no significant difference of the two groups.The intubation 2min,5min after extubation and extubation blood pressure,heart rate and cough incidence of L group of patients after were lower than that of C group.Conclusion The administration outside of tracheal tubes for neurosurgery can reduce cardiovascular responses after intubation and extubation and the incidence of cough.