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白细胞介素-27与类风湿关节炎研究进展 被引量：2

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摘要 RA是以侵蚀性滑膜炎为特点的一种自身免疫病,病因未明,可能与遗传、感染、环境因素均有关,诸多研究表明多种细胞因子参与了RA的发病过程.IL-27是IL-6家族细胞因子的最新成员,介导一系列的免疫反应,和IL-6、IL-12、IL-23一样,它们的配体在结构上存在着相似性,与RA炎密切相关.
作者 洪春梅 李忆农
机构地区 福建医科大学福总临床医学院福州总医院风湿内分泌科 福建医科大学附属福建武警总队医院风湿免疫科
出处 《中华风湿病学杂志》 CAS CSCD 北大核心 2014年第6期425-427,共3页 Chinese Journal of Rheumatology
关键词 白细胞介素-27 类风湿关节炎 IL-6家族 细胞因子 自身免疫病 IL-12 IL-23 环境因素
分类号 R593.22 [医药卫生—内科学]
  • 相关文献

参考文献22

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二级参考文献18

  • 1秦立新,张林,陈远林,杨一芬.类风湿性关节炎活动期几种急性时相反应蛋白的变化[J].实用预防医学,2005,12(2):306-307. 被引量：2
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  • 6Yoshimura T, Takeda A, Hamano S, et al. Two-sided roles of IL-27: induction of Thl differentiation on naive CD4+ cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on activated CD4CF cells partially through STAT3-dependent mechanism [J]. Immunol, 2006, 20(177): 5377-5385.
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共引文献10

同被引文献21

引证文献2

二级引证文献7

中华风湿病学杂志
2014年 第6期

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